I just wanted to let you know that the Sonic Comic Encyclopedia actually has a little panel with the Locke meme face (Locke and Lara with baby Knuckles). I doubt that's a coincidence. No scan, sadly, just a heads up.
I saw it! I don’t know if that was a conscious choice or the only panel they had with a shot of baby Knuckles and family worth using, but it gave me a chuckle.